FORM 6-K SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 of the Securities Exchange Act of 1934 August 02, 2005 Commission File Number 001-14978 SMITH & NEPHEW plc (Registrant's name) 15 Adam Street London, England WC2N 6LA (Address of registrant's principal executive offices) [Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.] Form 20-F X Form 40-F --- --- [Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1).] Yes No X --- --- [Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7).] Yes No X --- --- [Indicate by check mark whether by furnishing the information contained in this Form, the registrant is also thereby furnishing information to the Commission pursuant to Rule 12g3-2 (b) under the Securities Exchange Act of 1934.] Yes No X --- --- If "Yes" is marked, indicate below the file number assigned to the registrant in connection with Rule 12g3-2 (b) : 82- n/a. SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. Smith & Nephew plc (Registrant) Date: August,02, 2005 By: /s/ Paul Chambers ----------------- Paul Chambers Company Secretary NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Name of company Smith & Nephew plc 2. Name of shareholder having a major interest Barclays plc 3. Please state whether notification indicates that it is in respect of holding of the shareholder named in 2 above or in respect of a non-beneficial interest or in the case of an individual holder if it is a holding of that person's spouse or children under the age of 18 Non-beneficial interest 4. Name of the registered holder(s) and, if more than one holder, the number of shares held by each of them Barclays Capital Nominees Limited 1,786,178 Barclays Trust Co & Others 7,705 Barclays Trust Co E99 36 Barclays Trust Co R69 11,920 Chase Nominees Limited 516,711 Gerrard Nominees Limited 106,805 Greig Middleton Nominees Limited 725,595 Greig Middleton Nominees Limited 83,050 Investors Bank and Trust Co. 1,822,057 Investors Bank and Trust Co. 26,702 Investors Bank and Trust Co. 13,652 Investors Bank and Trust Co. 183,430 Investors Bank and Trust Co. 179,950 Investors Bank and Trust Co. 170,324 Investors Bank and Trust Co. 50,148 Investors Bank and Trust Co. 252,423 Investors Bank and Trust Co. 1,088,628 Investors Bank and Trust Co. 212,486 Investors Bank and Trust Co. 9,915 Investors Bank and Trust Co. 283,518 Investors Bank and Trust Co. 4,769,060 JP Morgan (BGI Custody) 289,097 JP Morgan (BGI Custody) 55,799 JP Morgan (BGI Custody) 517,519 JP Morgan (BGI Custody) 113,241 JP Morgan (BGI Custody) 10,019,295 JP Morgan (BGI Custody) 15,268 JP Morgan (BGI Custody) 38,843 JP Morgan Chase Bank 60,469 JP Morgan Chase Bank 9,587 JP Morgan Chase Bank 788 JP Morgan Chase Bank 161,182 JP Morgan Chase Bank 182,061 JP Morgan Chase Bank 125,539 JP Morgan Chase Bank 495,553 JP Morgan Chase Bank 99,632 JP Morgan Chase Bank 8,045 JP Morgan Chase Bank 9,258 JP Morgan Chase Bank 26,806 JP Morgan Chase Bank 131,787 JP Morgan Chase Bank 38,362 JP Morgan Chase Bank 28,881 Mellon Trust - Boston & SF 130,277 Mitsubishi Trust International 6,073 R C Greig Nominees Limited 3,604,046 R C Greig Nominees Limited 1,436,699 R C Greig Nominees Limited 280,892 R C Greig Nominees Limited 186,261 R C Greig Nominees Limited GP1 425,605 R C Greig Nominees Limited SA1 334,125 Reflex Nominees Limited 1,500 State Street 16,123 State Street Boston 80,662 State Street Boston 610,405 Zeban Nominees Limited 84,248 5. Number of shares / amount of stock acquired 31,924,221 6. Percentage of issued class 3.40% 7. Number of shares / amount of stock disposed 8. Percentage of issued class 9. Class of security Ordinary Shares of 12 2/9p 10. Date of transaction 11. Date company informed 02.08.2005 12. Total holding following this notification 31,924,221 13. Total percentage holding of issued class following this notification 3.40% 14. Any additional information 15. Name of contact and telephone number for queries Kate Cummins - Company Secretarial Assistant 020 7960 2251 16. Name and signature of authorised company official responsible for making this notification Kate Cummins - Company Secretarial Assistant Date of notification 02.08.2005 The FSA does not give any express or implied warranty as to the accuracy of this document or material and does not accept any liability for error or omission. 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