UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. 3)* CELL THERAPEUTICS, INC Common Stock, no par value per share (Title of Class of Securities) 150934107 CUSIP Number March 31, 2004 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: |_| Rule 13d-1(b) |X| Rule 13d-1(c) |_| Rule 13d-1(d) *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). Continued on following pages Page 1 of 13 Pages Exhibit Index: Page 12 SCHEDULE 13G CUSIP NO. 150934107 Page 2 of 12 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) PARAMOUNT CAPITAL ASSET MANAGEMENT, INC. 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| 3 SEC Use Only 4 Citizenship or Place of Organization DELAWARE 5 Sole Voting Power Number of 0 Shares Beneficially 6 Shared Voting Power Owned By 822,301 Each Reporting 7 Sole Dispositive Power Person 0 With 8 Shared Dispositive Power 822,301 9 Aggregate Amount Beneficially Owned by Each Reporting Person 822,301 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * |_| 11 Percent of Class Represented By Amount in Row (9) 1.63% 12 Type of Reporting Person * CO * see instructions before filling out SCHEDULE 13G CUSIP NO. 150934107 Page 3 of 12 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ARIES SELECT, LTD. 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| 3 SEC Use Only 4 Citizenship or Place of Organization CAYMAN ISLANDS 5 Sole Voting Power umber of 0 Shares Beneficially 6 Shared Voting Power Owned By 465,195 Each Reporting 7 Sole Dispositive Power Person 0 With 8 Shared Dispositive Power 465,195 9 Aggregate Amount Beneficially Owned by Each Reporting Person 465,165 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * |_| 11 Percent of Class Represented By Amount in Row (9) 0.92% 12 Type of Reporting Person * CO * see instructions before filling out SCHEDULE 13G CUSIP NO. 150934107 Page 4 of 12 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) LINDSAY A. ROSENWALD, M.D. 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| 3 SEC Use Only 4 Citizenship or Place of Organization UNITED STATES 5 Sole Voting Power Number of 1,579,510 Shares Beneficially 6 Shared Voting Power Owned By 822,301 Each Reporting 7 Sole Dispositive Power Person 1,579,510 With 8 Shared Dispositive Power 822,301 9 Aggregate Amount Beneficially Owned by Each Reporting Person 2,401,811 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * |_| 11 Percent of Class Represented By Amount in Row (9) 4.76% 12 Type of Reporting Person * IN * see instructions before filling out SCHEDULE 13G CUSIP NO. 150934107 Page 5 of 12 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ARIES SELECT I LLC 2 Check the Appropriate Box If a Member of a Group * a. |_| b. |X| 3 SEC Use Only 4 Citizenship or Place of Organization DELAWARE 5 Sole Voting Power Number of 0 Shares Beneficially 6 Shared Voting Power Owned By 293,474 Each Reporting 7 Sole Dispositive Power Person 0 With 8 Shared Dispositive Power 293,474 9 Aggregate Amount Beneficially Owned by Each Reporting Person 293,474 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * |_| 11 Percent of Class Represented By Amount in Row (9) 0.58% 12 Type of Reporting Person * CO * see instructions before filling out SCHEDULE 13G CUSIP NO. 150934107 Page 6 of 12 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) ARIES SELECT II LLC 2 Check the Appropriate Box If a Member of a Group * b. |_| c. |X| 3 SEC Use Only 4 Citizenship or Place of Organization DELAWARE 5 Sole Voting Power Number of 0 Shares Beneficially 6 Shared Voting Power Owned By 63,632 Each Reporting 7 Sole Dispositive Power Person 0 With 8 Shared Dispositive Power 63,632 9 Aggregate Amount Beneficially Owned by Each Reporting Person 63,632 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * [ ] 11 Percent of Class Represented By Amount in Row (9) 0.13% 12 Type of Reporting Person * CO * see instructions before filling out PAGE 7 OF 12 039998.0003 NEW YORK 357623 v1 ITEM 1(A) NAME OF ISSUER: Cell Therapeutics, Inc. (the "Issuer"). ITEM 1(B) ADDRESS OF THE ISSUER'S PRINCIPAL EXECUTIVE OFFICES: 201 ELLIOTT AVE W, STE 400 SEATTLE, WA 98119 PHONE: 206-270-7100 ITEM 2(A) NAME OF PERSON FILING: This statement is filed on behalf of Paramount Capital Asset Management, Inc. ("Paramount Capital"), Aries Select, Ltd. ("Aries Select"), Aries Select I LLC ("Aries I"), Aries Select II LLC ("Aries II") and Lindsay A. Rosenwald, M.D. ("Dr. Rosenwald" and collectively, the "Reporting Persons"). Dr. Rosenwald is an investment banker, venture capitalist, fund manager and sole stockholder and chairman of Paramount Capital. Paramount Capital is the managing member to each of Aries I and Aries II and the investment manager to Aries Select. ITEM 2(B) ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE: The address of the principal business office of Paramount Capital, Aries I, Aries II and Dr. Rosenwald is 787 Seventh Avenue, 48th Floor, New York, New York, 10019. The address of the principal business office of Aries Select is c/o Fortis Fund Services Cayman Limited, Grand Pavilion Commercial Center, 802 West Bay Road, Grand Cayman, Cayman Islands. ITEM 2(C) CITIZENSHIP: 1) Paramount Capital is a Subchapter S corporation incorporated in Delaware; 2) Aries Select is a Cayman Islands exempted company; 3) Aries I and Aries II are Delaware limited liability companies; 4) Dr. Rosenwald is a citizen of the United States. ITEM 2(D) TITLE OF CLASS OF SECURITIES: Common Stock (the "Shares"). ITEM 2(E) CUSIP NUMBER: 150934107 ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO RULE 13D-1(B), OR 13D-2(B) OR (C), CHECK WHETHER THE PERSON FILING IS A: This Item 3 is not applicable. PAGE 8 OF 12 ITEM 4. OWNERSHIP: ITEM 4(A) AMOUNT BENEFICIALLY OWNED: Each of the Reporting Persons may be deemed the beneficial owner of the following number of Shares: (i) Paramount Capital may be deemed to own 822,301Shares, which includes the Shares owned by Aries Select, Aries I and Aries II. (ii) Aries Select may be deemed the beneficial owner of 465,195 Shares, which includes 423,595Shares and options to purchase 41,600 Shares (iii) Aries I may be deemed the beneficial owner of 293,474 Shares, which includes 261,474 Shares and options to purchase 32,000 Shares (iv) Aries II may be deemed the beneficial owner of 63,632 Shares which includes 57,232 Shares and options to purchase 6,400 Shares (v) Dr. Rosenwald may be deemed the beneficial owner of 2,401,811 Shares as follows: (a) all shares described in (i) - (iv) above; and (b) 1,544,510 Shares and warrants to purchase 35,000 Shares owned directly by Dr. Rosenwald. ITEM 4(B) PERCENT OF CLASS: Please see Item 11 of each cover page. PAGE 9 OF 12 ITEM 4(C) NUMBER OF SHARES AS TO WHICH SUCH PERSON HAS: (i) Sole power to vote or direct the vote: Please see Item 5 of each cover page (ii) Shared power to vote or to direct the vote Please see Item 6 of each cover page (iii) Sole power to dispose or to direct the disposition of Please see Item 7 of each cover page (iv) Shared power to dispose or to direct the disposition of Please see Item 8 of each cover page ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS: None of the the reporting parties own greater than 5% of any class of securities of the issuer. ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON: Not applicable. ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY: This Item 7 is not applicable. ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP: This Item 8 is not applicable. ITEM 9. NOTICE OF DISSOLUTION OF GROUP: This Item 9 is not applicable. ITEM 10. CERTIFICATION: By signing below each of the Reporting Persons certifies that, to the best of such person's knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the Issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purpose or effect. PAGE 10 OF 12 SIGNATURES After reasonable inquiry and to the best of my knowledge and belief, the undersigned certifies that the information set forth in this statement is true, complete and correct, as of this April 16, 2004. LINDSAY A. ROSENWALD, M.D. PARAMOUNT CAPITAL ASSET MANAGEMENT, INC. By; /s/ Lindsay A. Rosenwald By: /s/ Lindsay A. Rosenwald ------------------------ ----------------------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT, LTD. By: Paramount Capital Asset Management, Inc. Its: Investment Manager By: /s/ Lindsay A. Rosenwald ----------------------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT I LLC By: Paramount Capital Asset Management, Inc. Its Managing Manager By: /s/ Lindsay A. Rosenwald ----------------------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT II LLC By: Paramount Capital Asset Management, Inc. Its Managing Manager By: /s/ Lindsay A. Rosenwald ----------------------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman PAGE 11 OF 12 EXHIBIT INDEX Page No. -------- A. Joint Filing Agreement, dated as of April 16, 2004 by and among Paramount Capital Asset Management, Inc., Aries Select, Ltd., Aries Select I LLC, Aries Select II, LLC, and Lindsay A. Rosenwald, M.D................... 13 PAGE 12 OF 12 EXHIBIT A JOINT FILING AGREEMENT The undersigned hereby agree that the statement on Schedule 13G with respect to the Common Stock of Cell Therapuetics, Inc. dated as of April 16, 2004, is, and any amendments thereto (including amendments on Schedule 13D) signed by each of the undersigned shall be, filed on behalf of each of us pursuant to and in accordance with the provisions of Rule 13d-1(k) under the Securities Exchange Act of 1934. LINDSAY A. ROSENWALD, M.D. PARAMOUNT CAPITAL ASSET MANAGEMENT, INC. By; /s/ Lindsay A. Rosenwald By: /s/ Lindsay A. Rosenwald ------------------------ ----------------------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT, LTD. By: Paramount Capital Asset Management, Inc. Its Investment Manager By: /s/ Lindsay A. Rosenwald ----------------------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT I LLC By: Paramount Capital Asset Management, Inc. Its: Managing Manager By: /s/ Lindsay A. Rosenwald ----------------------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman ARIES SELECT II LLC By: Paramount Capital Asset Management, Inc. Its: Managing Manager By: /s/ Lindsay A. Rosenwald ----------------------------------------- Name: Lindsay A. Rosenwald, M.D. Title: Chairman