================================================================================


                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                                 ______________


                                  SCHEDULE 13G
                                 (RULE 13D-102)

 INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13D-1 (B) (C),
                AND (D) AND AMENDMENTS THERETO FILED PURSUANT TO
                                  RULE 13D-2(B)

                               (AMENDMENT NO. 1)*


                                Pharmasset, Inc.
--------------------------------------------------------------------------------
                                (Name of Issuer)

                    Common Stock, $0.001 par value per share
--------------------------------------------------------------------------------
                         (Title of Class of Securities)

                                    71715N106
--------------------------------------------------------------------------------
                                 (CUSIP Number)

                                December 31, 2008
--------------------------------------------------------------------------------
             (Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

     [ ]  Rule 13d-1(b)
     [ ]  Rule 13d-1(c)
     [X]  Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).
================================================================================

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CUSIP NO.  71715N106                   13G                           PAGE 2 OF 9
====================                                                 ===========


ITEM 1(A).    NAME OF ISSUER:
              ---------------
              Pharmasset, Inc. (the "Issuer").

ITEM 1(B).    ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
              ------------------------------------------------
              303-A College Road East, Princeton, New Jersey 08540.

ITEM 2(A).    NAME OF PERSONS FILING:
              -----------------------
              This statement is filed by TVM IV GmbH & Co. KG ("TVM IV"); TVM IV
              Management GmbH & Co. KG, the managing limited partner and
              investment committee of TVM IV ("TVM IV Management"); TVM V Life
              Science Ventures GmbH & Co. KG ("TVM V LS"); TVM V Life Science
              Ventures Management GmbH & Co. KG, the managing limited partner
              and investment committee of TVM V LS ("TVM V LS Management"); TVM
              Capital GmbH ("TVM Capital"), the sole general partner of TVM IV,
              TVM IV Management, TVM V LS and TVM V LS Management; Friedrich
              Bornikoel ("Bornikoel"), John DiBello ("DiBello"), Alexandra Goll
              ("Goll"), Helmut Schuhsler ("Schuhsler") and Bernd Seibel
              ("Seibel"), who are members of TVM Capital (collectively the "TVM
              Capital Managers"); Hans Schreck ("Schreck"), who, together with
              the TVM Capital Managers, are limited partners of, and serve as
              members of the investment committee of TVM IV Management, Dr. Gert
              Caspritz ("Caspritz") who is a former member of the investment
              committees of TVM IV Management and TVM V LS Management and
              Christian Claussen ("Claussen") who is a former member of the
              investment committee of TVM IV Management (collectively, the "TVM
              IV Managers"); and Hubert Birner ("Birner"), Mark Cipriano
              ("Cipriano"), Stefan Fischer ("Fischer"), Axel Polack ("Polack")
              and David Poltack ("Poltack"), who, together with the TVM Capital
              Managers, are limited partners of, and serve as members of the
              investment committee of TVM V LS Management (collectively, the
              "TVM V LS Managers"). The persons named in this paragraph are
              referred to individually herein as a "Reporting Person" and
              collectively referred to as the "Reporting Persons."

ITEM 2(B).    ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE:
              ------------------------------------------------------------
              The principal business address for TVM IV, TVM IV Management, TVM
              Capital, TVM V LS, TVM V LS Management, Birner, Bornikoel,
              Fischer, Goll, Polack, Schreck, Schuhsler and Seibel is
              Maximilianstrasse 35/Eingang C, 80539 Munchen, Germany. The
              principal business address for Cipriano, DiBello and Poltack is
              101 Arch Street, Suite 1950, Boston, MA 02110. The principal
              business address for Claussen is Sankt-Pauls-Platz 9, 80336
              Munchen, Germany. The principal business address for Caspritz is
              111 Devonshire Street, Suite 730, Boston, MA 02109.

ITEM 2(C).    CITIZENSHIP:
              ------------
              TVM Capital is a German limited liability company. TVM IV, TVM IV
              Management, TVM V LS, and TVM V LS Management are German limited
              partnerships. Cipriano, DiBello and Poltack are citizens of the
              United States. Birner, Bornikoel, Caspritz, Claussen, Fischer,
              Goll, Polack, Schreck and Seibel are citizens of Germany.
              Schuhsler is a citizen of Austria.

ITEM 2(D).    TITLE OF CLASS OF SECURITIES:
              -----------------------------
              Common Stock, $0.001 par value per share (the "Common Stock").

ITEM 2(E).    CUSIP NUMBER:
              -------------
              71715N106


====================                                                 ===========
CUSIP NO.  71715N106                   13G                           PAGE 3 OF 9
====================                                                 ===========

ITEM 3.       IF THIS STATEMENT IS FILED PURSUANT TO RULE 13D-1(B), OR 13D-2(B)
              -----------------------------------------------------------------
              OR (C), CHECK WHETHER THE PERSON FILING IS A:
              ---------------------------------------------

              Not applicable.

ITEM 4.       OWNERSHIP.
              ----------
              Not applicable.

ITEM 5.       OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS.
              ---------------------------------------------
              Each Reporting Person has ceased to own beneficially five percent
              (5%) or more of the Issuer's outstanding Common Stock.





















====================                                                 ===========
CUSIP NO.  71715N106                   13G                           PAGE 4 OF 9
====================                                                 ===========


                                    SIGNATURE

     After reasonable inquiry and to the best of my knowledge and belief, each
of the undersigned certifies that the information set forth in this statement is
true, complete and correct.


Date: February 17, 2009


TVM CAPITAL GMBH

By: /s/ Friedrich Bornikoel
    --------------------------------
    Name:  Friedrich Bornikoel
    Title: Managing Partner

By: /s/ Bernd Seibel
    --------------------------------
    Name:  Bernd Seibel
    Title: Chief Financial Officer


TVM IV GMBH & CO. KG

    By: /s/ Stefan Fischer
        --------------------------------
        Name:  Stefan Fischer
        Title: Managing Limited Partner

    By: /s/ Bernd Seibel
        --------------------------------
        Name:  Bernd Seibel
        Title: Managing Limited Partner


TVM IV MANAGEMENT GMBH & CO. KG

By: TVM Capital GmbH, its General Partner

    By: /s/ Stefan Fischer
        --------------------------------
        Name:  Stefan Fischer
        Title: Authorized Signatory

    By: /s/ Bernd Seibel
        --------------------------------
        Name:  Bernd Seibel
        Title: Authorized Signatory


TVM V LIFE SCIENCE VENTURES GMBH & CO. KG

By: /s/ Stefan Fischer
    --------------------------------
    Name:  Stefan Fischer
    Title: Managing Limited Partner

By: /s/ Bernd Seibel
    --------------------------------
    Name:  Bernd Seibel
    Title: Managing Limited Partner



====================                                                 ===========
CUSIP NO.  71715N106                   13G                           PAGE 5 OF 9
====================                                                 ===========


TVM V LIFE SCIENCE VENTURES MANAGEMENT GMBH & CO. KG

By: TVM Capital GmbH, its General Partner

    By: /s/ Stefan Fischer
        --------------------------------
        Name:  Stefan Fischer
        Title: Authorized Signatory

    By: /s/ Bernd Seibel
        --------------------------------
        Name:  Bernd Seibel
        Title: Authorized Signatory


/s/ Hubert Birner
------------------------------
Hubert Birner


/s/ Friedrich Bornikoel
------------------------------
Friedrich Bornikoel


/s/ Gert Caspritz
------------------------------
Gert Caspritz


/s/ Mark Cipriano
------------------------------
Mark Cipriano


/s/ Christian Claussen
------------------------------
Christian Claussen


/s/ John J. DiBello
------------------------------
John J. DiBello


/s/ Stefan Fischer
------------------------------
Stefan Fischer


/s/ Alexandra Goll
------------------------------
Alexandra Goll


/s/ Axel Polack
------------------------------
Axel Polack


/s/ David Poltack
------------------------------
David Poltack


====================                                                 ===========
CUSIP NO.  71715N106                   13G                           PAGE 6 OF 9
====================                                                 ===========


/s/ Hans Schreck
------------------------------
Hans Schreck


/s/ Helmut Schuhsler
------------------------------
Helmut Schuhsler


/s/ Bernd Seibel
------------------------------
Bernd Seibel



























====================                                                 ===========
CUSIP NO.  71715N106                   13G                           PAGE 7 OF 9
====================                                                 ===========

                                                                       EXHIBIT 1
                                                                       ---------

                                    AGREEMENT

Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the
undersigned hereby agree that only one statement containing the information
required by Schedule 13G need be filed with respect to the ownership by each of
the undersigned of shares of Common Stock of Pharmasset, Inc.

EXECUTED as a sealed instrument this 17th day of February, 2009.

TVM CAPITAL GMBH

By: /s/ Friedrich Bornikoel
    --------------------------------
    Name:  Friedrich Bornikoel
    Title: Managing Partner

By: /s/ Bernd Seibel
    --------------------------------
    Name:  Bernd Seibel
    Title: Chief Financial Officer


TVM IV GMBH & CO. KG

    By: /s/ Stefan Fischer
        --------------------------------
        Name:  Stefan Fischer
        Title: Managing Limited Partner

    By: /s/ Bernd Seibel
        --------------------------------
        Name:  Bernd Seibel
        Title: Managing Limited Partner


TVM IV MANAGEMENT GMBH & CO. KG

By: TVM Capital GmbH, its General Partner

    By: /s/ Stefan Fischer
        --------------------------------
        Name:  Stefan Fischer
        Title: Authorized Signatory

    By: /s/ Bernd Seibel
        --------------------------------
        Name:  Bernd Seibel
        Title: Authorized Signatory


TVM V LIFE SCIENCE VENTURES GMBH & CO. KG

By: /s/ Stefan Fischer
    --------------------------------
    Name:  Stefan Fischer
    Title: Managing Limited Partner

By: /s/ Bernd Seibel
    --------------------------------
    Name:  Bernd Seibel
    Title: Managing Limited Partner



====================                                                 ===========
CUSIP NO.  71715N106                   13G                           PAGE 8 OF 9
====================                                                 ===========


TVM V LIFE SCIENCE VENTURES MANAGEMENT GMBH & CO. KG

By: TVM Capital GmbH, its General Partner

    By: /s/ Stefan Fischer
        --------------------------------
        Name:  Stefan Fischer
        Title: Authorized Signatory

    By: /s/ Bernd Seibel
        --------------------------------
        Name:  Bernd Seibel
        Title: Authorized Signatory


/s/ Hubert Birner
-------------------------------
Hubert Birner


/s/ Friedrich Bornikoel
-------------------------------
Friedrich Bornikoel


/s/ Gert Caspritz
-------------------------------
Gert Caspritz


/s/ Mark Cipriano
-------------------------------
Mark Cipriano


/s/ Christian Claussen
-------------------------------
Christian Claussen


/s/ John J. DiBello
-------------------------------
John J. DiBello


/s/ Stefan Fischer
-------------------------------
Stefan Fischer


/s/ Alexandra Goll
-------------------------------
Alexandra Goll


/s/ Axel Polack
-------------------------------
Axel Polack


/s/ David Poltack
-------------------------------
David Poltack


====================                                                 ===========
CUSIP NO.  71715N106                   13G                           PAGE 9 OF 9
====================                                                 ===========



/s/ Hans Schreck
-------------------------------
Hans Schreck


/s/ Helmut Schuhsler
-------------------------------
Helmut Schuhsler


/s/ Bernd Seibel
-------------------------------
Bernd Seibel