New York, USA – January 26, 2022 – Creative BioMart, the world leader in serving science, today announced an update to its CAR-T Cell targets portfolio to assist scientists worldwide with their cancer research. A variety of antigen proteins are prepared to provide a large selection of ready-to-use options.
CAR T cell therapy is an immunotherapy that can change the patient’s own T cells, allowing them to recognize and attack cancer. T cells are taken from the patient’s blood. Genes for special receptors that bind to a protein on a patient’s cancer cells are then added in the laboratory.
Identification of the target occurs before and is a prerequisite for CAR-T cell therapy. In order to avoid damage to healthy tissues caused by CAR-T cell therapy, the target must be limited to tumor cells. To date, ideal therapeutic effects have been achieved against a variety of tumor-associated antigens (TAAs).
However, it is difficult to find an ideal biomarker as an anti-tumor target, which is highly expressed on the surface of tumor cells, but rarely expressed on healthy cells. More commonly, selected biomarkers are expressed on both tumor cells and healthy cells, with significant expression level discrimination. This is why close attention should be paid to on-target-off-tumor cytotoxicity of CAR-T cell therapy.
To satisfy the fast-growing need in CAR-T development, Creative BioMart has prepared a variety of antigen proteins to provide a large selection of ready-to-use options. In addition, the company also bring to the market some special proteins that have been difficult to express or purify.
Some of the CAR-T targets molecules provided by Creative BioMart are listed below:
TNFRSF17, IL3RA, SDC1, CD19, MS4A1, CD22, CD20, BCMA, HER2, CD33, CD38, EGFR, EPCAM, GPC3, PDCD1, CD274, CA9, FAP, CD23, CD276, CD133, FOLR1, FOLH1, GPNMB, etc.
For more information on the Targets of CAR-T Cell Therapy, please visit https://www.creativebiomart.net/Targets-of-CAR-T-Cell-Therapy.htm.
For research use only. Not intended for any clinical use.
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Company Name: Creative BioMart
Contact Person: Caroline Green
Email: Send Email
Phone: 1-516-855-7709
Country: United States
Website: https://www.creativebiomart.net
