A liver transplant, also known as a hepatic transplant, is a surgical procedure that is performed when a patient's liver is not capable of performing basic functions, such as synthesizing proteins, carbohydrates, and fats. After the kidney, the liver is the second most frequently transplanted major organ, indicating the seriousness of the liver disease. Despite the fact that the majority of liver transplant operations use livers from deceased donors, it is still possible to obtain a liver from a living person as well (allograft). Current liver transplant demand is substantial, however only critically ill patients are considered for transplants, and these patients are selected based on their critical condition.

NEWARK, DE / ACCESSWIRE / December 3, 2024 / The Liver Transplantation Market 2023 to 2033 is witnessing significant growth, reflecting advancements in medical technology and rising prevalence of liver-related diseases. In 2023, the market is valued at USD 1,409.8 million and is projected to reach USD 2,653.4 million by 2033, marking a robust CAGR of 6.5% over the forecast period.

The increasing incidence of liver disorders such as cirrhosis and hepatocellular carcinoma is a major driver. According to WHO, nearly 2 million deaths annually are attributed to liver diseases globally. This has spurred a demand for innovative transplantation techniques and improved donor-recipient matching systems.

Government and private sector investments in healthcare infrastructure and organ transplantation programs are creating lucrative opportunities. Additionally, the emergence of minimally invasive techniques and the integration of AI-based tools in organ matching and post-operative care have revolutionized the liver transplantation landscape.

As the market expands, Asia-Pacific and North America are expected to dominate due to increased healthcare spending and better awareness programs, while advancements in biotechnology continue to drive the innovation curve.

What Factors are Driving Growth of the Liver Transplantation Market?

As hepatitis A, B, and C incidence increases worldwide, the liver transplantation market is expected to grow in the coming years. A major driving force in the liver transplantation market is the advancement of treatment and the increase in adoption as the most effective method of managing end-stage liver disease.

Additionally, reimbursement policies are likely to become increasingly favorable in the near future, leading to a growth in liver transplantation. The fact that organ transplantation is becoming an increasingly popular treatment for organ failure is one of the most significant factors contributing to the growth of the market.

During the coming years, the market will experience a great deal of growth due to the rise of passive lifestyles, bad eating habits, excessive drinking, and drug abuse being among the main factors that are driving the market to grow. Various causes of liver failure among the global population as well as the growing geriatric population have increased the demand for liver transplants in various regions

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Key Takeaways from Market Study

• Market Size in 2023: USD 1,409.8 million

• Market Size in 2033: USD 2,653.4 million

• CAGR (2023-2033): 6.5%

• Key Growth Regions: North America, Asia-Pacific

"The liver transplantation market is entering a dynamic growth phase with the integration of cutting-edge technologies such as AI and robotic surgeries. While the increasing burden of liver diseases presents challenges, the market's rapid adaptation to patient needs and regulatory frameworks ensures a promising future. Public-private collaborations will play a pivotal role in accelerating accessibility and affordability." Says Sabyasachi Ghosh (Associate Vice President at Future Market Insights, Inc.)

Restricting Factors for the Global Liver Transplantation Market?

There are several risks associated with this procedure, including severe bleeding and negative reactions that can be life-threatening, which is a restraint on its use. Several other diseases that can occur as a result of transplants, such as diabetes, high cholesterol, and diarrhea, may impact the market's growth. Staying in a hospital for a long period of time can be expensive, which can hamper the growth of the liver transplantation market.

In addition, there are several factors that contributed to the sharp decline in the market's revenue not only in recent years, but also in the future, including the shortage of primary intensive care units, protective equipment, and blood products during transplantation. Over the forecast period, however, liver transplantation market growth can be hindered by a shortage of liver donors, increased waiting lists for liver transplants, and an increase in hospitalization time and costs. As a result, liver transplantation will see a decline in market share in the near future.

Component Insights

The liver transplantation market comprises key components such as immunosuppressive drugs, surgical equipment, and post-operative care services. Among these, immunosuppressive drugs hold the largest share due to their essential role in preventing graft rejection.

Growth Drivers

• Advanced Surgical Techniques: Minimally invasive procedures reduce patient recovery times and risks.

• Rising Awareness: Growing public understanding of liver health and the importance of transplantation.

• Supportive Regulations: Policies facilitating faster approvals of new
  portable medical devices and drugs.

Emerging Innovators Are Leading a Transformation in Liver Transplantation

A new wave of innovative start-ups, particularly in Western markets, is reshaping the liver transplantation landscape. These companies are introducing cutting-edge medical devices aimed at streamlining transplant procedures, ultimately offering significant benefits to both donors and recipients.

Several European firms are pioneering advancements in the preservation of livers donated by both living and deceased individuals. Traditionally, the usable window for a liver after removal from the body is just 12 hours, beyond which the organ is no longer viable for transplantation. Efforts are underway to extend this critical time frame, providing more flexibility and improving patient outcomes.

HepaTx, a U.S.-based company, is making strides in the field of regenerative medicine. They are developing stem cell-based therapies as alternatives to liver transplants, targeting patients with late-stage liver diseases. According to their data, only one in thirty-three patients in need of a liver transplant receives an organ in time, highlighting the ongoing challenges in the donor-recipient imbalance despite significant government investments in healthcare.

Recent Advancements in Liver Transplantation

A ground breaking procedure took place in September 2023 at Jaslok Hospital and Research Center in Mumbai, where a single liver was used to save two lives through a split cadaver liver donation surgery. This method divides the liver into two parts, enabling both an adult and a pediatric patient to benefit from the transplant simultaneously.

In another notable development, the Liver4Life team at the University of Zurich has created an innovative blood perfusion machine. This device has the potential to extend the preservation time of a liver to 72 hours, a significant improvement over the previous 12-15 hours. The normothermic perfusion machine mimics the function of a human body by pumping blood to the liver, while supplying essential nutrients and medications to keep the organ in optimal condition before transplantation. This breakthrough has the potential to dramatically improve the viability of donor livers, making a substantial impact on the field.

In-Depth Market Analysis: A Complete Report
https://www.futuremarketinsights.com/reports/liver-transplantation-market

Key Market Players

• Allosource

• Conatus Pharmaceuticals Inc.

• Digna Biotech S.L.

• Dompe Farmaceutici S.p.A.

• Isogenis, Inc.

• RedHill Biopharma Ltd.

• Thompson Surgical

• Integra Life Sciences

• Baxter International Inc.

• XVIVO

• VirTech Bio

• Vital Therapies

• HepaTx

• Humedics

Regional Analysis of Liver Transplantation Market

• North America: Largest market share with advanced healthcare infrastructure.

• Europe: Strong government support and rising organ donation rates.

• Asia-Pacific: Fastest growth driven by increasing medical tourism and awareness.

• Middle East & Africa: Emerging market due to improved healthcare facilities.

Key Segments Profiled in the Global Liver Transplantation Market

By Treatment Type:

• Liver Transplantation Surgery

• Post-Surgery Anti-Rejection Treatment

• Cyclosporine

• Tacrolimus

• Sirolimus Prednisone Azathioprine

• Mycophenolate Mofetil

By End Use:

• Hospitals

• Adult Liver Transplantation Centers

• Ambulatory Surgical Centers

By Region:

• North America

• Latin America

• Europe

• Asia Pacific

• The Middle East and Africa

Author

Sabyasachi Ghosh (Associate Vice President at Future Market Insights, Inc.) holds over 12 years of experience in the Healthcare, Medical Devices, and Pharmaceutical industries. His curious and analytical nature helped him shape his career as a researcher.

Identifying key challenges faced by clients and devising robust, hypothesis-based solutions to empower them with strategic decision-making capabilities come naturally to him. His primary expertise lies in areas such as Market Entry and Expansion Strategy, Feasibility Studies, Competitive Intelligence, and Strategic Transformation.

Holding a degree in Microbiology, Sabyasachi has authored numerous publications and has been cited in journals, including The Journal of mHealth, ITN Online, and Spinal Surgery News.

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