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                                Biogen Idec Inc.
                (Name of Registrant as Specified In Its Charter)

                                  Carl C. Icahn
                             Dr. Alexander J. Denner
                                Dr. Anne B. Young
                          Professor Richard C. Mulligan
                               Vincent J. Intrieri
                                Keith A. Meister
                                 David Schechter
                                Icahn Partners LP
                          Icahn Partners Master Fund LP
                        Icahn Partners Master Fund II LP
                        Icahn Partners Master Fund III LP
                         High River Limited Partnership
                             Hopper Investments LLC
                                 Barberry Corp.
                           Icahn Enterprises G.P. Inc.
                         Icahn Enterprises Holdings L.P.
                                   IPH GP LLC
                               Icahn Capital L.P.
                                Icahn Onshore LP
                                Icahn Offshore LP
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    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

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On June 9, 2008,  investment  funds controlled by Carl C. Icahn sent a letter to
shareholders  of Biogen Idec Inc. The letter is attached hereto as Exhibit I and
is incorporated herein by reference.





                                                                       EXHIBIT I
                                                                       ---------

                                ICAHN PARTNERS LP
                              ICAHN MASTER FUND LP
                             ICAHN MASTER FUND II LP
                            ICAHN MASTER FUND III LP
                          767 FIFTH AVENUE, 47TH FLOOR
                            NEW YORK, NEW YORK 10153


June 9, 2008

Dear Fellow Shareholders:

We need your vote for our slate of directors.

Our nominees will seek to ensure that Biogen Idec's Board is involved in what is
happening at the Company and will look out for shareholder interests.

As has become  clear to us, and  contrary to Biogen's  earlier  statements,  the
current board did not "develop and execute" nor adequately  "supervise" the sale
process in the fall of 2007.

We say this based on our review of the  Company's  books and  records  that were
turned over to us under Court  Order.  What is  apparent,  however,  is that the
Company  allowed outside  advisors and  management,  with little Board input, to
design and execute the sale process.  It appears that the Board was not aware of
the  details of the sale  process  until the process  was almost  concluded.  In
particular,  the Board  does not  appear to have been  aware of the  prohibition
against  bidders  talking with Elan prior to submitting  firm and binding offers
until December 9, 2007 - three days before they publicly terminated the process!
We encourage you to read the results of our  examination of the Company's  books
and  records  titled "The  Biogen  Sale  Process - A Story of Missteps  and Poor
Design" which is attached to this letter and which provides a detailed  analysis
of 222 pages of the Company's books and records concerning the sale process.

Unfortunately  for shareholders of Biogen,  the bidders that participated in the
2007 sale  process  are now locked  into  lengthy  standstill  agreements  which
preclude such bidders from talking to the Company about an acquisition. However,
if in the future it became  apparent  that one of the  bidders  from the fall of
2007 was  interested  in paying a large  premium for the  Company,  our nominees
could potentially persuade the incumbent directors to waive the prohibition.

Importantly,  we also believe there are a number of operational  areas where our
nominees  can work with  management  and the  existing  directors to improve the
Company.  If elected,  you can be confident  that our nominees will  immediately
seek to  prioritize  four key  issues.  We  intend  to work on these  issues  in
cooperation with the whole board and management.

First,  our  nominees  will  make it  clear  that  we  prioritize  research  and
development as a central  component to the ethos of Biogen.  We view research as
central to Biogen's  value and we would like to increase  overall  investment in
research and  development.  Our nominees  have the expertise to review all major
research  activities  in order to determine  whether there are projects that may
not have received adequate attention and if so, to urge increased  investment in
those projects.

Second,  we would seek to take  measures to improve  employee  morale.  Biogen's
employees  are  critical  to the  Company's  success  and we would  endeavor  to
increase their faith in the company.

Third,  our nominees will seek to improve the  relationship  between  Biogen and
Elan, as well as with other business partners,  including  Genentech (who Biogen
is currently engaged in arbitration against in connection with a dispute under a
collaboration agreement between the two companies).  We believe that an improved
relationship  between Biogen and both Elan and Genentech could benefit all three
companies' shareholders, and most importantly,  Tysabri and Rituxan patients. In
this  regard,  you  should  know  that  Professor  Richard  Mulligan  and I were
influential in improving the relationship between ImClone and Bristol Myers.

Finally,  our nominees will seek to review spending on areas outside of research
with the view that  corporate  and  capital  expenses  can be  reduced  by smart
analysis of needs and negotiating better pricing. Again, we intend to do this in
cooperation with the rest of the board.

Based on the documents we received in  connection  with our lawsuit in Delaware,
it is our view that the current board and management have  mischaracterized  how
the sale process was designed and conducted, and that the Board was probably not
sufficiently engaged in the design,  conduct or supervision of the sale process.
Particularly,  because of the Board's  failures with regard to the sale process,
we urge you to support our nominees so that you will be confident  that at least
three  board  members  are looking  out for  shareholder  interests  and will be
engaged in important strategic issues at the Company.

Your vote is important, no matter how many or how few shares you own.

To vote your shares, please sign, date and return the GOLD proxy card by mailing
it in the  pre-addressed,  stamped  envelope.  You may  also  vote by  phone  or
Internet by following the instructions on the proxy card.

Thank you for your support.

                                            Very truly yours,


                                            /s/ Alexander J. Denner
                                            -----------------------
                                            Alexander J. Denner
                                            Managing Director





          THE BIOGEN SALE PROCESS - A STORY OF MISSTEPS AND POOR DESIGN

For at least the past several months, we have publicly discussed our belief that
Biogen's  efforts to sell itself in the fall of 2007  failed  because of the way
the sale process was designed and conducted --  specifically,  we were concerned
about the prohibition in the sale process against  potential  bidders talking to
the Company's key  third-party  partners  until after the  submission of binding
offers,  a prohibition  that we believe  doomed the sale process to failure from
the outset. The Company has repeatedly and publicly denied our critiques, and on
one occasion,  even referred to us as advancing "wild  conspiracy  theories."(1)
Having  now  prevailed  in a  lawsuit  against  the  Company  to gain  access to
documents  that would  support our  suspicions  regarding the design of the sale
process, we write to share what we have learned with you.

As you may already  know,  on March 28,  2008,  we requested  certain  books and
records from the Company relating to the Company's efforts to sell itself in the
fall of 2007.  When the  Company  refused  to  voluntarily  provide  us with the
documents we requested,  we were forced to bring a lawsuit in the Delaware Court
of Chancery to compel the Company to provide us with the documents.

Throughout  the lawsuit,  the Company  appeared to us as if it had  something to
hide and thus vigorously opposed giving us access to the documents.  However, in
a bench ruling at the conclusion of trial on May 19, 2008, Chancellor William B.
Chandler III of the Delaware  Court of Chancery,  ruled in our favor and against
Biogen,  and ordered the Company to produce  various  documents to us concerning
Biogen's failed sale process.

Pursuant to the Court's order, on May 29, 2008, the Company provided us with 222
pages of documents regarding the failed sale process. The following day, May 30,
2008, Biogen made all of those documents  available to the public through an SEC
filing. In that filing, the Company asserted (among other things) that: "[t]hese
documents are consistent  with Biogen Idec's prior public  statements  about the
[sales] Process and demonstrate that the [sales] Process was  comprehensive  and
fair."(2)

Having  reviewed the  documents  produced by the Company,  we have reached a far
different conclusion than the Company asserts in its May 30, 2008 SEC filing. In
short,  the  documents  confirm what we have  believed for several  months:  The
Company,  in  conjunction  with its  advisors,  and with  very  little,  if any,
involvement from the Board, designed a process that was, from the outset, doomed
to fail. Specifically,  and as we discuss in more detail below, the documents do
not appear to support (i) the Company's  publicly stated position that the Board
was fully involved,  well-informed,  and closely supervised the sale process and
its design - instead,  it appears that management and financial advisors led the
process with very little Board involvement,  (ii) public comments of Jim Mullen,
the Company's chief executive  officer,  regarding how the process was conducted
with regards to when bidders  could hold  discussions  with Elan and what impact
such discussions would have on previously  submitted  binding offers,  and (iii)
Jim Mullen's  public  explanations as to why the process  failed.  Finally,  the
documents  appear to suggest  that a late-stage  bidder  dropped out of the sale
process after asking for, and seemingly  being denied,  an  opportunity  to talk
with Elan.

_________________________
(1)  "Icahn  Files  Suit To Gain  Access  To  Biogen  Records,"  April 8,  2008,
     Reuters.
(2)  The Company's  DEFA14A,  filed with the Securities and Exchange  Commission
     (the "SEC") on May 30, 2008.





WAS THE BOARD FULLY  INVOLVED AND  WELL-INFORMED  OF THE SALE PROCESS?  DID THEY
CLOSELY SUPERVISE THE SALE PROCESS AND ITS DESIGN?

In response to our  critiques  concerning  how the  process  was  designed,  the
Company has used the following  words to indicate the Board's  involvement  with
the sale process: it "developed",  "executed", "authorized,  supervised" and was
"fully  informed" of the design and conduct of the sale process.(3) The produced
documents do not support  these  claims.  Instead,  those  documents  reveal the
following details about the sale process.

On October 12, 2007,  the day Biogen  publicly  announced the sale process,  the
Board met and "directed  management to explore  whether third parties would have
an interest in acquiring the  Company..."(4) The minutes of that meeting make no
mention  of any  discussion  regarding  the  design of the sale  process  or any
mention of the Board  approving any specific sale process  procedures.  Further,
the Company has not  produced any minutes  predating  October 12, 2007 (in fact,
they  have  not  produced  any   documents   predating   the  October  12,  2007
announcement) that show how the Board was involved in designing the process.  We
believe  that the Order of the Court of Chancery  called for the  production  of
pre-October  12, 2007  documents,  which  leads us to conclude  that no relevant
documents exist.

Based on the  documents  produced  to us,  the Board does not appear to have met
following the October 12, 2007 meeting  until  November 8, 2007 - almost a month
later! And yet, shareholders are being told that the Board "supervised" the sale
process  when  they did not even meet for the month  immediately  following  its
public announcement. Similar to the minutes of the October 12, 2007 meeting, the
minutes of the November 8, 2007 meeting still make no mention of how the process
would be designed or any authorization of any specific  procedures.  In fact, it
was not until  December 9, 2007,  almost two months  after the process was first
publicly  announced  (and two  days  after  final  proposals  were to have  been
submitted by bidders) that the Board minutes  reference the fact that  potential
bidders had been precluded from speaking with Elan until after the submission of
a final and binding proposal.(5)

On  December  12,  2007,  the  Board  appears  to have  had its  first  and only
substantive  discussion  concerning  how the process was designed and conducted.
Unfortunately,  December  12, 2007 was, of course,  two months after the process
was first announced,  five days after final proposals were due, and the same day
Biogen announced the sale process had failed!

Why has the Company  made public  comments  suggesting  Board  involvement  with
designing and  supervising  the process when, in fact,  the minutes of the Board
meetings during the sale process do not support this position?

_________________________
(3)  See the Company's  DEFA14A,  filed on February 6, 2008.  See also, a letter
     dated  April 4, 2008 from Eliza W. Swann of  Shearman  & Sterling  LLP,  to
     Andrew Langham and Marc Weitzen of Icahn Associates Corp.  (which was filed
     as Joint Exhibit No. 34 in High River Limited Partnership, et al. v. Biogen
     Idec Inc., Delaware Court of Chancery, C.A. No. 3677-CC).
(4)  See the Company's  Minutes of a Special  Meeting of the Board of Directors,
     dated October 12, 2007, filed by the Company as DEFA14A, on May 30, 2008.
(5)  See the Company's  Minutes of a Special  Meeting of the Board of Directors,
     dated December 9, 2007,  filed by the Company as DEFA14A,  on May 30, 2008.
     (6)





WHEN  COULD  BIDDERS  HOLD   DISCUSSIONS  WITH  ELAN?  WHAT  IMPACT  WOULD  SUCH
DISCUSSIONS HAVE ON PREVIOUSLY  SUBMITTED FIRM AND BINDING OFFERS?  WHAT DID THE
BOARD KNOW?

On November 20, 2007, the Company's  advisors,  on behalf of Biogen,  sent a bid
process  letter to one or more  potential  bidders.  In that  letter,  potential
bidders  were  advised that in order to continue in the sale process they needed
to submit "a firm and binding  offer" by December  7,  2007.(6)  The bid process
letter also required that the firm and binding proposal: (i) should include firm
commitment  letters and not be subject to  financing  contingences,  (ii) should
include a statement that the bidder "will  execute" the merger  agreement in the
form  provided by Biogen or as marked up by the  bidder,  (iii)  should  include
"best  and  final  financial  terms"  and  (iv)  should  not be  subject  to the
completion of additional business, legal or other due diligence. The bid process
letter also stated that a "prevailing  prospective  purchaser would be given the
exclusive  opportunity to engage in  discussions"  with Elan  regarding  Tysabri
collaboration  and that "any such discussions would take place prior to entering
into the [merger  agreement]."  It does not say  anything  about the  prevailing
bidder being able to further negotiate  financial or other terms following those
discussions.

Read in conjunction,  the above  requirements  and procedures of the bid process
letter,  in particular the requirement that a bidder state it "will execute" the
merger agreement, the requirement that there be no due diligence conditions, the
requirement  that  firm  commitment  letters  be  obtained,   and  perhaps  most
importantly,  that  discussions  with Elan would be  limited  to one  prevailing
purchaser after proposals have been submitted but before the merger agreement is
executed, could have led a bidder to conclude that regardless of what it learned
in discussions  with Elan,  that since the bidder would have agreed "to execute"
the  agreement,  the bidder would  thereafter be obligated to execute the merger
agreement  without  any further  opportunity  to adjust its  financial  or other
terms!

Over the past several months,  Jim Mullen, has repeatedly made comments that are
wholly  inconsistent with the November 20, 2007 bid process letter. For example,
on January 7, 2008 at the JPMorgan Healthcare Conference Jim Mullen stated:

         And at the end [of the sale  process]  we  asked  parties  to  submit a
         binding  offer  and  a  marked  up  contract  contingent  only  on  the
         resolution  of  change  and  [sic]  control  agreements.  And  then the
         acquirer or if there were several very close  companies  would have had
         direct   negotiations  with  Elan  and  Genentech  before  executing  a
         definitive agreement.  So this last part I think sounds a lot different
         from what I've heard and have seen written out there.(7)

Jim  Mullen  is  correct  about one thing - what he  described  at the  JPMorgan
Healthcare  Conference is certainly a lot  different  from the November 20, 2007
bid process letter sent on the Company's behalf.

Contrary  to Jim  Mullen's  comments  above,  the bid  process  letter  does not
explicitly  provide that  resolution of change and control  agreements with Elan
and Genentech  would be a condition to the "firm and binding  proposal" that was
required by the bid process  letter.  The bid process  letter  actually makes it
very clear that proposals "should not be subject to the completion of additional
business,  legal or other  due  diligence."  Furthermore,  Jim  Mullen's  public
comments  seem to suggest  that  several  companies  could be  permitted to have
discussions  with  Elan and  Genentech,  when in fact,  the bid  process  letter
provides  that  only "a  prevailing  prospective  purchaser  will be  given  the
exclusive  opportunity to engage in discussions  with  representatives  of Elan"
prior to entering into the agreement  (emphasis  added).(8)  Finally,  and again
contrary to Jim Mullen's  public  comments  above (in which he states  potential
bidders would have direct  negotiations with Genentech),  the bid process letter
does not mention Genentech at all!

_________________________
(6)  See the letter from Merrill Lynch and Goldman  Sachs to potential  bidders,
     dated November 20, 2007, filed by the Company as DEFA14A, on May 30, 2008.
(7)  See the JPM Transcript, filed by the Company as DEFA14A, on May 30, 2008.
(8)  See the letter from Merrill Lynch and Goldman  Sachs to potential  bidders,
     dated November 20, 2007, filed by the Company as DEFA14A, on May 30, 2008.





Although the Board met on November  18, 2007,  two days prior to the date of the
bid  process  letter,  the Board  minutes  from that  meeting  do not in any way
suggest  that the bid  process  letter,  or the  contents of that  letter,  were
discussed.  In fact,  based on the  documents  produced and Jim Mullen's  public
comments,  it is unclear whether the Board or Jim Mullen knew anything about the
contents of the bid process letter.

Based on the  December  9, 2007 Board  minutes,  on  December 9, 2007 Jim Mullen
informed the Board that a bidder "had been advised that they would be invited to
speak with Elan after submission of [the bidder's]  proposal and that they could
revise their proposal after speaking with Elan" (emphasis added).(9) Why would a
bidder have been advised of this when it is in direct  contradiction  of the bid
process letter? Did Jim Mullen not know that his public comments  describing the
sale process at the JPMorgan Healthcare Conference, as well as the advice to the
Board that a potential  bidder could revise its proposal  following  discussions
with  Elan,  were all in  direct  contradiction  of the  terms  set forth in his
Company's  bid  process  letter?  Did Jim  Mullen and the Board not know how the
Company's sale process was designed per the bid process letter?

At the December 9, 2007 Board meeting the Board did in fact request that "during
such meeting"  (presumable a reference to an upcoming  Board meeting on December
12, 2007)  management and advisors  should review with the Board the entire sale
process in thorough detail.(10) Shockingly, two months into the process, this is
the first time that any Board  minutes  provided to us reflect  any  substantive
inquiry by the Board as to the details of the sale process!

Finally,  on June 3, 2008, the Company sent a letter to shareholders in which it
stated:

         Contrary to Mr. Icahn's inaccurate  suggestion,  any bidder that wished
         to make a proposal to acquire the company would have had an opportunity
         to speak with our partners BEFORE incurring  financing  commitment fees
         or executing a binding agreement.(11)

How does the Company  reconcile  this position with their own bid process letter
dated November 20, 2007, which  unambiguously  requires bidders to "include firm
commitment  letters  from  your  financing  sources"?  Perhaps  Biogen  has  had
different  experiences,  but generally,  commitment  fees are incurred when firm
commitment letters are issued.

Clearly,  and even as recently  as June 3, 2008,  Biogen  continues  to miss the
point as to discussions with Elan.  Although it is awfully kind to allow bidders
to talk with partners before executing a binding agreement; it is not so kind to
fail to assure bidders in the bid process letter that following such discussions
the bidders would have an opportunity to negotiate the financial and other terms
of the merger agreement!

_________________________
(9)  See the letter from Merrill Lynch and Goldman  Sachs to potential  bidders,
     dated November 20, 2007, filed by the Company as DEFA14A, on May 30, 2008.
(10) See the Company's  Minutes of a Special  Meeting of the Board of Directors,
     dated December 9, 2007,  filed by the Company as DEFA14A,  on May 30, 2008.
     In the  version  of the  December  9, 2007  minutes  publicly  filed by the
     Company,  Biogen's  outside  attorneys  redacted the Board's  request for a
     review of the sale process  procedures.  However,  under  pressure from our
     attorneys, the Company later removed certain redactions.
(11) See the Company's letter to shareholders,  dated June 3, 2008, filed by the
     Company as DEFA14A, on June 3, 2006.





JIM MULLEN'S PUBLIC  EXPLANATIONS AS TO WHY THE PROCESS FAILED ARE NOT SUPPORTED
BY THE DOCUMENTS

Jim Mullen has publicly  commented that the sale process failed,  not because of
its design, but (in one of his accounts) because of "market  conditions" and (in
another of his accounts)  because the "perceived risk profile of Tysabri at this
time is simply too great."(12) If these are the reasons the process failed, then
why were these factors never discussed at Board meetings? The documents produced
to us by the Company do not support Jim Mullen's  position,  but they do support
our position:  that this process failed because of its design, and specifically,
the prohibition  against bidders talking  directly with Elan prior to submitting
an offer.

WHY WAS A LATE-STAGE  BIDDER DENIED ACCESS TO ELAN?  WHY DID THE BOARD NOT GRANT
SUCH ACCESS TO PERMIT THE BIDDER TO MAKE A BID?

On  December  12,  2007,  the Board met,  and Mr. Jack Levy,  of Goldman  Sachs,
provided an update of the sale  process.(13)  Mr. Levy  advised the Board that a
potential  bidder  had  requested  a meeting  with Elan  prior to  submitting  a
proposal.  The  minutes  from  this  Board  meeting  strongly  suggest  that the
potential  bidder was not granted  such a meeting;  instead  Goldman  Sachs made
certain  representations  regarding  Elan  to  the  potential  bidder  --  as if
representations  made by bankers about a critical  business  partner should have
given the bidder sufficient  comfort to submit its "firm and binding offer"! Not
surprisingly,  Mr. Levy further advised the Board that the potential  bidder did
not submit a final  proposal.  Why was a  late-stage  bidder who had been in the
process for close to two months  denied its  request to talk with Elan?  Did the
Board,  management and the Company's advisors not understand that such a failure
to accommodate a basic request by a seemingly  credible and serious bidder could
be fatal to that bidder's  interest?  If they did not know, they certainly found
out quickly when the bidder failed to submit a bid.

Jim  Mullen  has  stated  that  he  does  not  believe  the  sale  process,  and
specifically the confidentiality agreements that prohibited bidders from talking
with Elan and Genentech (without Biogen's consent),  "created any impediments to
the sale process, and that is something we specifically  reviewed with the Board
of Directors to ensure we were satisfied with that."(14)

We have concluded from the December 12, 2007 Board meeting minutes that at least
one  potential  bidder did not submit a bid because it was not permitted to talk
to Elan. It appears to us that the prohibition on discussions with Elan were not
only an impediment,  but were actually fatal, to at least one bidder's  interest
in the  process.  Jim Mullen  claims  that these  aspects  of the  process  were
"specifically  reviewed with the Board." Perhaps so, but such specific review is
wholly absent from the October,  November and December Board minutes!  And, even
assuming Jim Mullen's  claims are true, it only begs the  question:  why did the
Board not lift the  prohibition  and let the late-stage  bidder talk to Elan? If
the Board was truly  interested  in selling the Company,  it would have done so,
yet the minutes do not suggest that the Board even considered doing this.

In conclusion,  when the Court ordered  Biogen to produce books and records,  we
were  confident that a number of our beliefs would be confirmed.  Today,  we can
report to you that this is in fact the case.  Biogen's  books and  records  show
that:

     o    the Board had very  little  input in  designing  and  supervising  the
          process,

     o    it appears  at least one  potential  bidder was denied its  request to
          talk to Elan before  submitting  a firm and binding  offer,  which may
          have caused that bidder to walk away from the process, and

     o    a number of Biogen's subsequent  assertions  regarding the process are
          not consistent with their own documents!

_________________________
(12) Compare the transcript of the Company's fourth-quarter earnings call, filed
     by the Company as DEFA14A on February 6, 2008,  with the  Company's  May 8,
     2008  letter to  stockholders  regarding  the proxy  contest,  filed by the
     Company a DEFA14A on May 8, 2008.
(13) See the Company's  Minutes of a Special  Meeting of the Board of Directors,
     dated December 12, 2007, filed by the Company as DEFA14A, on May 30, 2008.
(14) See the Company's  fourth-quarter  earnings  call,  filed by the Company as
     DEFA14A on February 6, 2008.