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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 10-K/A

      |X| Annual Report Pursuant to Section 13 or 15(d) of the Securities
                              Exchange Act of 1934

                   For the fiscal year ended October 31, 2005

                                       OR

    |_| Transition Report Pursuant to Section 13 or 15(d) of the Securities
                              Exchange Act of 1934

                   For the transition period from ___ to ____.

                                     0-29230
                              (Commission File No.)

                       TAKE-TWO INTERACTIVE SOFTWARE, INC.
             (Exact name of Registrant as specified in its charter)

                Delaware                                     51-0350842
      (State or Other Jurisdiction                        (I.R.S. Employer
   of Incorporation or Organization)                     Identification No.)

    622 Broadway, New York, New York                            10012
(Address of principal executive offices)                     (zip code)

       Registrant's telephone number, including area code: (646) 536-2842

        Securities registered pursuant to Section 12(b) of the Act: None

           Securities registered pursuant to Section 12(g) of the Act:
                          Common Stock, $.01 par value

Indicate by check mark if the  registrant is a well-known  seasoned  issuer,  as
defined in Rule 405 of the Securities Act. Yes |X| No |_|

Indicate  by  check  mark if the  registrant  is not  required  to file  reports
pursuant to Section 13 or Section 15(d) of the Act. Yes |_| No |X|

Indicate by check mark whether the Registrant (1) has filed all reports required
to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during
the  preceding 12 months (or for such  shorter  period that the  Registrant  was
required  to file  such  reports)  and  (2)  has  been  subject  to such  filing
requirements for the past 90 days. Yes |X| No |_|

Indicate by check mark if disclosure of delinquent  filers  pursuant to Item 405
of Regulation  S-K is not contained  herein,  and will not be contained,  to the
best  of  the  Registrant's   knowledge,  in  definitive  proxy  or  information
statements  incorporated  by  reference  in Part  III of this  Form  10-K or any
amendment to this Form 10-K. |_|




Indicate  by check mark  whether  the  Registrant  is an  accelerated  filer (as
defined in Rule 12b-2 of the Act). Yes |X| No |_|

Indicate by check mark whether the  registrant is a shell company (as defined in
the Rule 12b-2 of the Act). Yes |_| No |X|

The aggregate  market value of the voting and  non-voting  common equity held by
non-affiliates computed by reference to the price at which the common equity was
last sold, or the average bid and asked price of such common  equity,  as of the
last  business day of the  Registrant's  most recently  completed  second fiscal
quarter was approximately $1,664,160,000.

As of February 22, 2006, there were 71,478,926 shares of the Registrant's common
stock outstanding.

Documents Incorporated by Reference:   None


                                      -2-


                                    PART III

Item 10. Directors and Executive Officers of the Registrant

      Following  is  information  with  respect to our  executive  officers  and
directors:

      Paul  Eibeler,  age 50, has been Chief  Executive  Officer of our  company
since January 2005,  and our President and a director of our company since April
2004. Mr. Eibeler was President of our company from July 2000 to June 2003 and a
director from December 2000 to February  2003.  Prior to that, Mr. Eibeler was a
consultant for Microsoft's Xbox launch team. From July 2003 to October 2003, Mr.
Eibeler was President  and Chief  Operating  Officer of Acclaim  Entertainment's
North America  Division,  a company engaged in publishing  video games and, from
1998  to  1999,  Mr.  Eibeler  served  as  Acclaim  North  America's   Executive
Vice-President and General Manager. Acclaim Entertainment filed a petition under
Chapter 11 of the United  States  Bankruptcy  Code in October  2004.  During the
seven years prior to that,  Mr.  Eibeler held various  executive  positions with
Impact,  Inc.,  a leading  supplier of licensed  toys and school  supplies.  Mr.
Eibeler is a director of Dwango North America  Corp.,  a publicly held developer
and distributor of entertainment content and applications for mobile phones. Mr.
Eibeler received a B.A. degree from Loyola College in 1978.

      Karl H. Winters,  age 47, has been Chief Financial  Officer of our company
since  February  2002.  From April 2000 to June 2001,  Mr. Winters was the Chief
Financial  Officer of ModelWire,  Inc., a company  engaged in marketing  imaging
database  products.  From September 1993 to December 1999, Mr. Winters served in
various  positions,  most  recently  as Vice  President  of Trace  International
Holdings,  Inc., a private  holding company that held  significant  interests in
United Auto Group,  Inc.,  a  consolidator  of new car  dealerships,  and Foamex
International Inc., a manufacturer of polyurethane products.  From 1993 to 1999,
Mr. Winters held executive positions at United Auto and Foamex, most recently as
United  Auto's Chief  Financial  Officer and  Executive  Vice  President.  Trace
International  filed a petition under Chapter 11 of the United States Bankruptcy
Code in July 1999. From 1983 to 1993, Mr. Winters was a Senior Audit Manager for
Coopers & Lybrand.  Mr.  Winters is a C.P.A.  and  received  an M.B.A.  from the
University of Michigan and a B.A. in business  economics with a concentration in
accounting from Calvin College.

      Samuel A. Judd,  age 48, has been Senior Vice  President  of Planning  and
Administration of our company since July 2004. Prior to joining our company, Mr.
Judd served as Chief  Financial  Officer and Senior Vice President of Operations
at the Simon & Schuster  division of Viacom from June 1998 to December 2003. Mr.
Judd received his B.A. in economics from Cornell  University and an M.B.A.  from
the University of Pennsylvania's Wharton School of Business.

      Oliver R. Grace,  Jr.,  age 51, has been a director  of our company  since
April 1997. Since 1990, Mr. Grace, a private investor,  has been the Chairman of
the Board of Moscow Cablecom Corp.  (formerly  known as Anderson  Group,  Inc.),
which provides  broadband  cable services to the city of Moscow.  Mr. Grace is a
general  partner of Anglo  American  Security Fund,  L.P., a private  investment
fund.  Mr.  Grace  received a B.A. in Business  Administration  from  Vanderbilt
University.

      Robert  Flug,  age 57, has been a director of our company  since  February
1998 and interim non-executive Chairman of the Board of Directors of our company
since  January 2006.  Mr. Flug has held various  executive  positions  with S.L.
Danielle Survivor  (formerly S.L.  Danielle),  a women's apparel company,  since
September 1987, most recently as President and Chief Executive Officer. Mr. Flug
received a B.S. in Business Administration from New York University.

      Todd Emmel, age 43, has been a director of our company since February 2002
and interim  Chairman of our Audit  Committee  since  January  2006.  Mr.  Emmel
previously  served as  Chairman of our Audit  Committee  from April 2004 to July
2004. Since August 2003, Mr. Emmel has served as Director,  Structured  Products
for John Hancock Financial Services, a financial and insurance services company.
From  November  1999 until June 2002,  Mr.  Emmel was a First Vice  President at
Ambac Assurance  Corporation,  a financial  insurance company.  From May 1999 to
November 1999, Mr. Emmel was Chief Credit Officer at Structured Credit Partners,
a private credit  arbitrage  firm.  From March 1998 to May 1999, Mr. Emmel was a
Managing  Director of DVI Private  Capital Group,  a private  equity fund.  From
April 1990 to March 1998,  Mr.  Emmel held  various  positions  at Union Bank of
Switzerland,  most recently as a Managing Director. Prior to this, Mr. Emmel was
an Associate at both Drexel  Burnham  Lambert,  from June 1988 to February 1990,
and at E.F. Hutton from July 1987 to February 1988. Mr. Emmel received an M.B.A.
from Carnegie Mellon University and a B.S. in accounting from Miami University.


                                      -3-


      Mark Lewis, age 56, has been a director of our company since May 2001. For
the fifteen years prior to February 2001, Mr. Lewis held various  positions with
Electronic  Arts,  Inc.,  a company  engaged in  publishing  video  games,  most
recently as Senior Vice  President of  International  Operations.  Mr. Lewis has
been a director of Muse  Communications  Corp., a broadband  technology company,
since  November  1997.  Mr. Lewis  received a B.A. in English and  graduated Cum
Laude from Yale University.

      Steven Tisch, age 57, has been a director of our company since April 2002.
Since 1986, Mr. Tisch has been an independent motion picture producer. Mr. Tisch
is the Oscar Award winning  producer of Forrest  Gump,  the 1994 winner for Best
Picture.  Since May 2000,  Mr.  Tisch has been a partner  of Escape  Artists,  a
private  independent film company,  and a director of Classic Media, an owner of
franchise  entertainment  properties.  Since  June  2002,  Mr.  Tisch has been a
director of Film Roman,  Inc., a publicly  held  television  and motion  picture
production company.  From 1976 to 1986, Mr. Tisch was a principal of Tisch/Avnet
Productions, a production company with credits such as Risky Business. Mr. Tisch
is a member of the  Board of  Directors  of the Tisch  School of the Arts at New
York University and The Geffen Theatre in Los Angeles. Mr. Tisch received a B.A.
in Sociology from Tufts University.

      Michael  J.  Malone,  age 61,  has been a director  of our  company  since
January  2006.  From May 2001  through  February  2005,  Mr.  Malone  served  as
non-executive  Chairman of Maxide  Acquisition,  Inc., a holding company for DMX
Music,  Inc.  (formerly AEI Music  Network,  Inc.), a supplier of music services
that he founded in 1971. On February 14, 2005,  Maxide  Acquisition,  Inc. filed
for Chapter 11  protection  with the U.S.  Bankruptcy  Court for the District of
Delaware. From 2001 through 2004, Mr. Malone served as non-executive Chairman of
DMX Music and,  from 1971 through 2001,  Mr.  Malone  served as Chief  Executive
Officer and non-executive  Chairman of AEI Music Network, Inc. From 1995 through
2005,  Mr.  Malone  served as  Chairman  of MTM  Management,  a  national  hotel
management  company.  Since 1985, Mr. Malone has served as Chairman of Erin Air,
Inc., a national jet charter  company based in Seattle.  Since 1999,  Mr. Malone
has  served  on the  Board  of  Directors  and  Audit  Committee  of  Expeditors
International of Washington,  Inc., a global  logistics  services  company.  Mr.
Malone  received  a B.A.  in  Business  Administration  from the  University  of
Washington.

      All  directors  listed  above  are  currently  serving a term of office as
directors which  continues until the next annual meeting of our  stockholders or
until their  successors  have been duly  elected and  qualified,  or until their
earlier death, resignation or removal.

      Director Independence.  The Board has determined that all of our company's
current  directors,  with the  exception  of Mr.  Eibeler  (our Chief  Executive
Officer  and  President)  have  met the  independence  requirements  of the NASD
Marketplace Rules applicable to companies whose securities are quoted on NASDAQ.

      Section 16(a) Beneficial Ownership Reporting Compliance. Based solely on a
review  of Forms 3, 4 and 5  furnished  to us with  respect  to our most  recent
fiscal year, we believe that all reporting  persons  currently  required to file
reports  under  Section  16 of the  Securities  Exchange  Act of 1934 filed such
reports on a timely  basis,  except  that Mr. Flug did not file two Forms 4 (two
transactions)  on a  timely  basis;  Mr.  Winters  did not  file one Form 4 (one
transaction)  on a timely basis;  Paul Eibeler did not file three Forms 4 (three
transactions) on a timely basis; and Oliver Grace did not file two Forms 4 (five
transactions) on a timely basis.

      Audit  Committee.  We have  established an Audit Committee of the Board of
Directors,  that is currently comprised of Messrs.  Emmel (Interim Chair), Grace
and Flug, each of whom is an  "independent"  director as defined under the rules
of the National Association of Securities Dealers, Inc.


                                      -4-


      Although the current  composition  of our Audit  Committee  satisfies  the
Audit Committee composition requirements of applicable NASDAQ Marketplace rules,
with the recent departure of the former Chair of our Audit Committee,  the Board
of Directors has determined that it no longer has an Audit Committee  member who
qualifies as a "financial  expert" under federal  securities  laws. The Board of
Directors  is  currently  seeking  to engage  an Audit  Committee  Chairman  who
qualifies as a "financial expert."

      Code of Ethics.  In March 2002,  we adopted a written  code of ethics,  as
amended,  that applies to all of our company's and our subsidiaries'  employees,
including  our  company's  principal  executive  officer,   principal  financial
officer,  principal  accounting officer or controller and any persons performing
similar  functions.  We will  provide a copy of our code of ethics to any person
without charge upon written request addressed to Take-Two Interactive  Software,
Inc., 622 Broadway, New York, New York 10012,  Attention:  Director of Corporate
Communications.

Item 11. Executive Compensation

      The following table sets forth the cash  compensation  paid by our company
during the fiscal years ended  October 31, 2003,  2004 and 2005 to those persons
who held the  position  of Chief  Executive  Officer and to the four most highly
compensated  executive officers other than our Chief Executive Officer,  each of
whom was serving at the end of the fiscal year ended  October 31, 2005 and whose
salary and bonus exceeded $100,000 (the "Named Executives"):



                                                 Summary Compensation Table
                                                     Annual Compensation                     Long-Term Compensation Awards
                                ---------------------------------------------------     ----------------------------------------
                                                                          Other         Restricted    Securities
                                                                          Annual           Stock       Underlying     All Other
                                 Year Ended                              Compen-          Awards        Options        Compen-
Name and Principal Position     October 31,   Salary($)     Bonus($)     sation(1)        ($)(2)         (#)(3)       sation ($)
---------------------------     -----------   ---------   -----------   -----------     -----------   -----------    -----------
                                                                                                
Paul Eibeler
Chief Executive Officer
 and President(4)                  2005         750,000       250,000            --       2,137,500        75,000          5,430(8)
                                   2004         330,000       300,000            --              --       450,000             --
                                   2003         296,153       650,000            --              --        75,000             --

Richard Roedel (5)                 2005         108,333       162,500            --              --            --        828,100(9)
                                   2004         360,000            --            --         229,250        72,000             --

Karl H. Winters
Chief Financial Officer            2005         385,000       100,000            --         397,800        50,000
                                   2004         325,000        15,000            --              --            --          9,640(10)
                                   2003         326,250       265,000            --              --            --             --
Gary Lewis (6)
                                   2005         600,000       500,000       197,500(11)          --            --         45,000(12)
                                   2004         326,538       250,000            --         638,400       217,500             --
                                   2003         258,027       132,923            --         101,080        30,000             --
Samuel Judd
Senior Vice President of
 Planning and
 Administration (7)                2005         385,000        55,000            --              --            --          4,511(13)
                                   2004          97,731            --            --         468,601       135,000             --


      (1) The aggregate value of benefits to be reported under the "Other Annual
Compensation" column did not exceed the lesser of $50,000 or 10% of the total of
annual salary and bonus reported for the Named Executives.


                                      -5-


      (2) The amounts  shown in this column  represent  the dollar  value of the
restricted  stock on the date of  grant.  In fiscal  2003,  Mr.  Lewis  received
restricted stock awards of 6,000 shares. In fiscal 2004, Messrs.  Roedel,  Lewis
and Judd received  restricted stock awards of 10,500,  30,000 and 22,500 shares,
respectively.  In fiscal 2005 Messrs.  Eibeler and Winters  received  restricted
stock awards of 75,000 and 20,000 shares, respectively. At October 31, 2005, the
number of shares of restricted stock held by Messrs.  Eibeler,  Roedel, Winters,
Lewis  and  Judd  was  75,000,   10,500,   20,000,  30,000  and  22,500  shares,
respectively,  and the value of such shares was $1,548,750,  $216,825, $413,000,
$619,500 and $464,625,  respectively.  Mr. Eibeler's shares were granted in June
2005,  one-third of which vest on each of June 2006, 2007 and 2008. Mr. Winter's
shares were  granted in October  2005,  one-third  of which vest on each of June
2006,  2007 and 2008.  Mr.  Roedel's  shares were  granted in March 2004 and are
fully  vested.  Mr.  Lewis'  shares were granted in April 2004 and May 2003,  of
which  30,000  shares are fully vested and 6,000  shares were sold.  Mr.  Judd's
shares were granted in July 2004 of which one-third of the shares vested in July
2005 and  one-third  vest in each of July  2006 and 2007. During the  restricted
period, all shares are entitled to receive dividends paid on the common stock.

      (3) Except for options to purchase  450,000 shares issued to Mr.  Eibeler,
all securities listed in the table were issued under stockholder-approved plans.

      (4) Mr.  Eibeler  rejoined  our company as  President  in April 2004,  and
became Chief Executive Officer in January 2005.

      (5) Mr. Roedel became Chief  Executive  Officer in April 2004 and resigned
from that position in January 2005.

      (6) Mr. Lewis became our Global Chief Operating  Officer in April 2004 and
resigned  from  that  position  in  January  2006.  Our  company  and Mr.  Lewis
subsequently  agreed to  terminate  Mr.  Lewis'  employment  with us and we have
reached an agreement in principle to pay Mr. Lewis approximately $500,000 during
the fiscal year ending October 31, 2006, in  consideration  of his agreement not
to compete with us or solicit our employees through January 3, 2007.

      (7) Mr. Judd became Senior Vice President in July 2004.

      (8)  Represents  $4,200 in  contributions  made by us under our  company's
401(k) Plan and $1,230 of term-life insurance premiums paid by us.

      (9)  Represents  payments made through January 31, 2006 in connection with
Mr. Roedel's resignation from the position of Chief Executive Officer in January
2005 pursuant to an agreement dated January 31, 2005.

      (10)  Represents  $4,200 in  contributions  made by us under our company's
401(k) Plan and $5,440 of term-life insurance premiums paid by us.

      (11) Includes a housing allowance of approximately $144,000.

      (12) Represents contributions made by us to a European pension plan.

      (13)  Represents  $2,961 in  contributions  made by us under our company's
401(k) Plan and $1,550 of term-life insurance premiums paid by us.

      The following table sets forth information  concerning  options granted in
the fiscal year ended October 31, 2005 to the Named Executives:



                                         Option Grants in Fiscal Year Ended October 31, 2005

                                         Individual Grants(1)
                                -------------------------------------------------------------------------------------------------
Name                            Number of           Percent of  Total       Exercise      Expiration    Potential Realizable
                                Securities          Options Granted to       Price          Date        Value at Assumed
                                Underlying          Employees in             ($/Sh)                     Annual Rates of Stock
                                Options             Fiscal Year (%)                                     Price Appreciation for
                                Granted (#)                                                             Option Term (2)
                                ----------          ---------------       ---------       ----------    -------------------------
                                                                                                             5%($)         10%($)
                                                                                                        -------------------------
                                                                                         
Paul Eibeler                        75,000                     2.55%       $  19.89        10/9/2010        412,143       910,728

Richard Roedel                          --                       --              --             -                --            --

Karl Winters                        50,000                     1.70%       $  19.89        10/9/2010        274,762       607,152

Gary Lewis                              --                       --              --             -                --            --

Samuel Judd                             --                       --              --             -                --            --



                                      -6-


      (1) All of the options have a term of five years and vest at various times
over the term of the options.

      (2) The potential  realizable value columns of the table illustrate values
that might be realized upon exercise of the options  immediately  prior to their
expiration,  assuming  the common  stock  appreciates  at the  compounded  rates
specified  over the term of the options.  These numbers do not take into account
provisions of certain options  providing for termination of the option following
termination of employment or  non-transferability of the options and do not make
any provision for taxes  associated  with  exercise.  Because  actual gains will
depend upon, among other things,  future  performance of the common stock, there
can be no assurance that the amounts reflected in this table will be achieved.

      The following table sets forth information concerning the value of options
exercised  during  the  fiscal  year  ended  October  31,  2005 and the value of
unexercised stock options held by the Named Executives as of October 31, 2005:



                              Aggregated Option Exercises in Last Fiscal Year and Fiscal Year End Values

                                                     Number of Securities
                     Shares                          Underlying                        Value of Unexercised
                   Acquired on        Value          Unexercised Options               In-the-Money Options
 Name              Exercise (#)     Realized ($)     at October 31, 2005 (#)           at October 31, 2005 ($)*
 ----              ------------     ------------     -----------------------           ------------------------

                                                     Exercisable    Unexercisable      Exercisable    Unexercisable
                                                     -----------    -------------      -----------    -------------
                                                                           
Paul Eibeler                 --               --         300,000          225,000           57,000               --

Richard Roedel               --               --         124,500               --          181,825               --

Karl Winters            225,500        3,431,930          64,500               --          161,685               --

Gary Lewis               52,500          556,375          97,500           90,000               --               --

Samuel Judd                  --               --          45,000           90,000               --               --



      *Year-end  values  for  unexercised  in-the-money  options  represent  the
positive  spread  between  the  exercise  price of such  options  and the fiscal
year-end market value of the common stock, which was $20.65 on October 31, 2005.

Director Compensation

      For the fiscal year ended  October 31, 2005,  each  non-employee  director
received a cash  retainer of $60,000.  In  addition  to cash  retainers,  during
fiscal  2005 Mr.  Flug  received  $25,000  for  serving as the  Chairman  of the
Compensation  Committee,  Mr. Emmel received  $20,000 for serving as Chairman of
the Corporate  Governance  Committee and Barbara Kaczynski  received $35,000 for
serving as Chair of the Audit Committee. Each member of the Audit Committee also
received  $10,000.  For the fiscal year ending  October 31, 2005,  each director
received a  restricted  stock award of 6,000  shares (Mr.  Flug  received  7,000
shares) vesting over a three-year period.

Employment Agreements

      We have entered into a three-year  employment  agreement with Paul Eibeler
commencing in May 2005 under which Mr. Eibeler devotes  substantially all of his
time to the business of our company as Chief  Executive  Officer and  President.
The agreement  provides for Mr.  Eibeler to receive an annual salary of $750,000
and an  annual  bonus  equal  to 100%  of the  salary  if  certain  agreed  upon
performance targets are achieved. Mr. Eibeler is also entitled to certain health
and life insurance benefits and an automobile allowance.  In addition to options
to purchase  300,000  shares that he received  when he became our  President  in
April 2004,  Mr.  Eibeler also  received a grant of 75,000  shares of restricted
stock  (vesting over a three-year  period) under the company's  Incentive  Stock
Plan. The agreement  provides for the company to pay Mr.  Eibeler's salary for a
period of twelve  months if his  employment  is terminated  without  cause.  The
agreement also provides for a lump-sum  payment equal to 1.5 times Mr. Eibeler's
salary and bonus if his employment is terminated upon a change of control.


                                      -7-


      We have  entered  into an  employment  agreement  as amended  with Karl H.
Winters, which currently expires in February 2007, subject to automatic renewals
for successive one-year periods, unless terminated earlier by either our company
or Mr.  Winters.  Mr. Winters  receives an annual salary of $385,000 and a bonus
equal to 50% of his salary,  provided that we achieve  certain  qualitative  and
quantitative  performance  criteria.  Mr.  Winters is also  entitled  to certain
health and life insurance  benefits and an automobile  allowance.  Mr.  Winters'
agreement   provides  that  if  his  employment  is  terminated   under  certain
circumstances,  including  without cause or in the event of a change of control,
he would be entitled to receive salary and other benefits for a period of twelve
months  following  the date of  termination  (which  amount  is  payable  in one
lump-sum if employment is terminated upon a change of control).

      We have entered into a three-year  employment  agreement  with Samuel Judd
commencing  July 2004.  The  agreement  provides that Mr. Judd is entitled to an
annual  salary of $385,000  and an annual bonus of  $275,000,  provided  that we
achieve certain qualitative and quantitative  performance criteria.  Mr. Judd is
also entitled to certain  health and life  insurance  benefits and an automobile
allowance.  Mr. Judd's  agreement  provides that if his employment is terminated
under certain circumstances, including without cause or in the event of a change
of control,  he would be entitled to receive salary and benefits for a period of
eighteen  months from the date of  termination  (which  amount is payable in one
lump-sum if employment is terminated upon a change of control).

      Each   employment    agreement   also   contains    confidentiality    and
non-competition provisions.


                                      -8-


Item 12.  Security  Ownership of Certain  Beneficial  Owners and  Management and
Related Stockholder Matters

      The following table sets forth certain information as of February 22, 2006
      relating to the  beneficial  ownership of shares of our  company's  common
      stock by (i) each person or entity who is known by us to own  beneficially
      5% or more of the outstanding common stock, (ii) each director, (iii) each
      of the Named Executives and (iv) all directors and executive officers as a
      group.



                                                                 Number of Shares of           Percentage of Outstanding
Name and                                                         Common Stock                  Common Stock
Address of Beneficial Owner(1)                                   Beneficially Owned(2)         Beneficially Owned
------------------------------------------------------------     ---------------------         -------------------------

                                                                                         
OppenheimerFunds, Inc.(3)                                                   17,448,018                             24.41

FMR Corp.(4)                                                                 9,128,300                             12.77

Glenview Capital Management, LLC(5)                                          7,883,372                             11.03

D.E. Shaw & Co., L.P.(6)                                                     6,371,255                              8.91

Wellington Management Company, LLP(7)                                        3,740,580                              5.23

Oliver R. Grace, Jr.(8)                                                        412,320                                 *

Robert Flug(9)                                                                 121,302                                 *

Mark Lewis(10)                                                                  36,000                                 *

Todd Emmel(11)                                                                  48,420                                 *

Steven Tisch(12)                                                                56,500                                 *

Richard W. Roedel(13)                                                          135,000                                 *

Karl H. Winters(14)                                                             64,500                                 *

Paul Eibeler(15)                                                               165,000                                 *

Gary Lewis(16)                                                                 172,500                                 *

Samuel Judd(17)                                                                 50,000                                 *

Michael J. Malone(18)                                                               --                                 *

All directors and executive officers
 as a group  (9 persons)(19)                                                   954,042                              1.32%



*     Less than 1%.

      (1) Unless  otherwise  indicated,  the address of each beneficial owner is
Take-Two Interactive Software, Inc., 622 Broadway, New York, New York 10012. The
address of  OppenheimerFunds,  Inc. is Two World Financial  Center,  225 Liberty
Street,  11th Floor, New York, New York 10281-1008.  The address of FMR Corp. is
82  Devonshire  Street,  Boston,  Massachusetts  02109.  The address of Glenview
Capital Management,  LLC is 399 Park Avenue, Floor 39, New York, New York 10022.
The  address of D.E.  Shaw & Co.,  L.P.  is 120 W. 45th  Street,  Tower 45, 39th
Floor, New York, New York 10036. The address of Wellington  Management  Company,
LLP is 75 State Street, Boston, Massachusetts 02109.


                                      -9-


      (2) Unless otherwise  indicated,  we believe that all persons named in the
table  have  sole  voting  and  investment  power  with  respect  to all  shares
beneficially  owned by them.  A person is deemed to be the  beneficial  owner of
securities  that may be acquired by such person within 60 days from February 10,
2006 upon the exercise of options.  Each beneficial owner's percentage ownership
is  determined  by assuming  that  options that are held by such person (but not
those  held by any other  person)  and which are  exercisable  within 60 days of
February  10, 2006 have been  exercised.  This table does not include  shares of
unvested restricted stock held by the persons named in the table.

      (3) Based on information  contained in a report on Schedule 13G filed with
the SEC on February 8, 2006.

      (4) Based on information  contained in a report on Schedule 13G filed with
the SEC on February 14, 2006.

      (5) Based on information  contained in a report on Schedule 13G filed with
the SEC on February 22, 2006.

      (6) Based on information  contained in a report on Schedule 13G filed with
the SEC on February 14, 2006.

      (7) Based on information  contained in a report on Schedule 13G filed with
the SEC on February 14, 2006.

      (8) Represents  272,820 shares owned of record by Anglo American  Security
Fund, L.P., of which Mr. Grace is a general partner,  6,000 shares of restricted
stock held by Mr. Grace and 133,500 shares underlying options held by Mr. Grace.
Does not include 12,000 unvested shares of restricted stock.

      (9) Represents  34,302 shares held by The Robert Flug Living Trust,  6,000
shares of restricted stock held by Mr. Flug and 81,000 shares underlying options
held by Mr. Flug. Does not include 13,000 unvested shares of restricted stock.

      (10)  Represents  30,000  shares  underlying  options and 6,000  shares of
restricted stock. Does not include 12,000 unvested shares of restricted stock.

      (11)  Represents  42,420  shares  underlying  options and 6,000  shares of
restricted stock. Does not include 12,000 unvested shares of restricted stock.

      (12)  Represents  52,500  shares  underlying  options and 4,000  shares of
restricted stock. Does not include 12,000 shares of unvested restricted stock.

      (13)  Represents  124,500 shares  underlying  options and 10,500 shares of
restricted stock.

      (14) Represents 64,500 shares underlying options.  Does not include 20,000
unvested shares of restricted stock.

      (15)  Represents  165,000  shares  underlying  options.  Does not  include
360,000  shares  issuable  upon the  exercise  of  unvested  options  and 75,000
unvested shares of restricted stock.

      (16)  Represents  142,500 shares  underlying  options and 30,000 shares of
restricted stock.

      (17)  Represents  options to purchase  45,000  shares and 5,000  shares of
restricted  stock.  Does not include 90,000 shares issuable upon the exercise of
unvested options and 10,000 unvested shares of restricted stock.

      (18) Does not include 25,000 shares issuable upon the exercise of unvested
options and 6,000 unvested shares of restricted stock.

      (19) Includes 613,920 shares issuable upon the exercise of options.


                                      -10-


      Securities Authorized for Issuance under Equity Compensation Plans.

      The following table provides  certain  information  with respect to all of
our company's equity compensation plans in effect as of October 31, 2005.



-----------------------------------------------------------------------------------------------------------
                                         (a)                      (b)                        (c)
-----------------------------------------------------------------------------------------------------------
        Plan Category           Number of securities       Weighted-average          Number of securities
                                  to be issued upon       exercise price of          remaining for future
                                     exercise of         outstanding options,        issuance under equity
                                outstanding options,     warrants and rights          compensation plans
                                 warrants and rights                                 (excluding securities
                                                                                    reflected in column (a))
-----------------------------------------------------------------------------------------------------------
                                                                           
Equity compensation plans
 approved by security holders         7,331,805(1)                $20.87                     2,211,067
-----------------------------------------------------------------------------------------------------------
Equity compensation plans not
 approved by security holders           803,751(2)                $17.27                            --
-----------------------------------------------------------------------------------------------------------
           Total                      8,135,556                   $20.48                     2,211,067
-----------------------------------------------------------------------------------------------------------


      (1) Includes  649,717 shares of restricted stock under the Incentive Stock
Plan.

      (2) Represents shares of common stock underlying individual option grants.
The options are five years in duration, expire at various dates between 2006 and
2009, contain anti-dilution provisions providing for adjustments of the exercise
price under certain  circumstances  and have termination  provisions  similar to
options granted under our stockholder approved plans.

Item 13. Certain Relationships and Related Transactions

Not applicable.

Item 14. Principal Accounting Fees and Services

                              INDEPENDENT AUDITORS

      PricewaterhouseCoopers  LLP  is  our  company's  independent  auditor  who
reported on our  financial  statements  for the fiscal  years ended  October 31,
2003, 2004 and 2005.

      The aggregate fees billed by our independent  auditor for the fiscal years
ended  October  31,  2004 and 2005 are set  forth  below.  The  Audit  Committee
believes that the services performed by our independent  auditor were compatible
with maintaining such auditor's independence.


                       2004         2005
                    ----------   ----------

Audit (1)           $1,904,000   $6,770,700
Audit Related (2)       44,000       37,500
Tax (3)                833,000    1,264,000
All Other                   --           --
                    ----------   ----------
Total               $2,781,000   $8,072,200


                                      -11-



      (1) Includes  financial  statement and statutory  audits.  For 2005,  this
category  also  includes  fees of  $3,702,000  in  connection  with the audit of
management's  assessment  of  internal  control  over  financial  reporting  and
PricewaterhouseCoopers  LLP's  audit  of our  internal  control  over  financial
reporting.

      (2) Includes benefit plan audits.

      (3) Includes tax compliance, advice and audit assistance.

      All services  provided to our company by our  independent  auditor must be
pre-approved by the Audit Committee. None of the Audit Related, Tax or All Other
services  listed above was approved by the Audit  Committee under a "de minimis"
exemption from pre-approval provided by applicable law.


                                   SIGNATURES

         Pursuant to the  requirements  of Section 13 or 15(d) of the Securities
Exchange Act of 1934 the registrant has duly caused the amendment to this report
to be signed on its behalf by the undersigned, thereunto duly authorized, in the
city of New York, state of New York, on this 27th day of February 2006.



                                         TAKE-TWO INTERACTIVE SOFTWARE, INC.

                                         By: /s/ Karl H. Winters
                                             -------------------------------
                                                 Karl H. Winters
                                                 Chief Financial Officer


                                      -12-


                                  EXHIBIT INDEX

EXHIBIT
-------

31.1  Certification  of Chief Executive  Officer  Pursuant to Section 302 of the
      Sarbanes-Oxley Act of 2002.

31.2  Certification  of Chief Financial  Officer  Pursuant to Section 302 of the
      Sarbanes-Oxley Act of 2002.


                                      -13-